Nexera-e
Comprehensive Two-Dimensional Liquid Chromatograph
Comprehensive 2D-LC methodology is a paradigm shift in liquid chromatography separation. By combining two independent separation modes orthogonally in combination with a dual-loop/dual-valve alternate switching design, the highest possible peak capacity is achieved.
The new Nexera-e is the ideal solution for the separation and characterization of most challenging and complex samples. It is particularly useful for the analysis of pharmaceutical impurities, proteolytic digests, food extracts, natural products and synthetic polymers.
Improved resolving power compared to conventional 1D-LC
How many peaks are co-eluted under one peak? The more complex the sample, along with a high percentage of similar compounds, there exists a high probability of co-eluting compounds found under single peaks.
Even though the co-eluting compounds may not be separated by mono-dimensional separation, an orthogonal two-dimensional system will provide the best possible result.
Features
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Comprehensive 2D-LC is a analytical methodology combining two independent separation modes orthogonally, greatly increasing separation efficiency.
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Shimadzu triple quadrupole mass spectrometers (TQMS) have the world-class polarity reversal speed (5 ms) and data capture speed (1.5 ms). In comprehensive 2D-LC analysis, the analysis time of second dimension is short, therefore the high-speed performance of the LC-MS affects the quality of the data.
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Comprehensive 2D-LC often requires complicated software operation for setting 1D and 2D analytical conditions. LabSolutions provides an easy parameter setting and contributes to the simple operation.
News / Events
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Shimadzu has released the Shim-pack Mix-HILIC, Chromatography Column for Hydrophilic Interactions
Comprehensive Analysis of Hydrophilic Metabolites in Metabolomics
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A new video has been released -Finding Out What Makes Things Sour-
Ever wondered what makes some foods sour? In this video we explore that question while also introducing one of Japan's traditional sour foods!
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New Nexera FV
Nexera FV and LabSolutions™ FV together form a new UHPLC system capable of monitoring flow synthesis and batch synthesis reactions, and automating formulation dissolution testing.
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Pharmaceutical and Biopharmaceutical has been updated.
Shimadzu Corporation has always been a reliable partner for the pharmaceutical industry. We provide comprehensive analytical solutions for all drug research analysis and productions and help companies to increase efficiency, reduce cost, and ensure drug safety and quality.
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On-line extraction and determination of targeted carotenoids from habanero red (Capsicum Chinese)
The on-line coupling between supercritical fluid extraction (SFE) and supercritical fluid chromatography (SFC), generate a powerful tool for the automatic extraction and detection of target compounds from food matrices. The on-line nature of the system, compared to off-line
approaches, improves run-to-run precision, enables the setting of batch-type applications, and reduces the risks of sample contamination. Supercritical carbon dioxide (CO2) presents unique characteristics, which make it an excellent solvent, it shows a relatively high density and
consequently, a high solvation power. -
New Nexera UC Prep
The Nexera™ UC Prep is a new preparative supercritical fluid chromatography (SFC) system that offers both the high basic performance developed for the previous Nexera UC model and original state-of-the-art preparative SFC technologies. It resolves a number of issues in preparative tasks, reducing labor and improving efficiency while fitting into pre-existing workflows.