Determination of Organic tin pesticides in fruits and vegetables by gas chromatography coupled to tandem mass spectrometry

Organic tin pesticides are often used to sterilize and kill of mites in fruits and vegetables. This kind of pesticides is dangerous substance with high toxicity, and some of them can cause cancers. The latest implementation of the food safety standards of china sets the maximum residue limit of azacyclotin and fenbutatin oxide in apple, organges, etc, which range from 0.1 mg/kg to 2.0 mg/kg. At present, the methods of detecting organic tin pesticides in China and abroad are mainly by GC and GC/MS. Because of the complexity of vegetable and fruit matrix, the method of GC and GC/MS is very complicated. A method for the simultaneous detection of azacyclotin, triphenylhydroxytin and fenbutatin oxide residues in fruits and vegetables was developed by pentylmagnesium bromide derivatization and GC-MS/MS. This method shows strong anti-interference capability, accuracy and high sensitivity to detect organic tin pesticides in fruits and vegetables.