Analysis of Potential Genotoxic Impurities in Active Pharmaceutical Ingredients (4) - Analysis of Haloalcohols and Glycidol Part 2 -
This Application Data Sheet reports on results with respect to a method for quantitating haloalcohols (2-chloroethanol, 2-bromoethanol, and 2-iodoethanol) and glycidol in an active pharmaceutical ingredient (API) utilizing the GCMS system. For the analysis conditions as well as the total ion current chromatogram and mass spectra for the haloalcohols and glycidol, refer to GCMS Application Data Sheet No. 41, "Analysis of Potential Genotoxic Impurities in Active Pharmaceutical Ingredients (3), Analysis of Haloalcohols and Glycidol Part 1."
- Content Type:
- Application
- Document Number:
- LAAN-J-MS-E042
- Product Type:
- Mass Spectrometry, Gas Chromatograph-Mass Spectrometry
- Keywords:
- haloalchohols glycidol impurities pharmaceutical ingredients, Pharmaceutical, Life Science, DMPK, ADME, Safety testing, GCMS-QP2010 Ultra
- Language:
- English
- File Name:
- jpo212204.pdf
- File Size:
- 128kb