Simultaneous Analysis of 477 Residual Pesticides in Agricultural Crops Using GC-MS/MS - Part 1

GC-MS/MS systems can measure more than 400 residual pesticides in foods. However, analyzing more than 400 pesticides simultaneously requires a short dwell time (data loading time) during MRM measurements, which results in problems with inadequate sensitivity and the tedious process of creating MRM measurement programs. Consequently, several different methods are used for target pesticides and the same sample is measured multiple times to analyze all components. That can decrease productivity, due to the time required for analyzing all the components involved in the large number of pesticides being inspected.

This Application Data Sheet describes a solution to these problems with the creation of a method for simultaneously analyzing 477 components and evaluating the resulting sensitivity and accuracy.