Automated Optimization of Chiral Separation Parameters Using Nexera UC Chiral Screening System
Chiral supercritical fluid chromatography (SFC) requires selecting a variety of separation parameters, such as columns and modifiers, which can involve large amounts of time and effort. This article describes using the Nexera UC chiral screening system to automatically optimize the large number of separation parameters by switching between up to 12 columns and various mixture ratios of four types of modifiers. This can significantly reduce the effort required.
- Content Type:
- Application
- Document Number:
- LAAN-A-LC-E271
- Product Type:
- Liquid Chromatography
- Keywords:
- Pharmaceuticals, Food, Supercritical, Chiral, Optical resolution, SFE, SFC, Method Scouting, Modifier, Omeprazole, Clinical research, Forensics, Food and Beverages, Hydrocarbon Processing Industry (Petrochemical, Chemical), Pharmaceutical, Life Science, Flavor and Fragrance, Cosmetics, Toiletry, Forensics, Toxicology, Drug test, Clinical research, Nexera UC
- Language:
- English
- File Name:
- jpl215034.pdf
- File Size:
- 1,576kb