Qualitative Analysis of Gossypol, Free Gossypol, and Gossypol Derivatives in the Cottonseeds By Electrospray Ionization Tandem Mass Spectrometry

Free gossypol and in cottonseed is a toxic chemical, which can affect human reproductive function, skin and stomach burning, nausea, vomiting, diarrhea, headache, coma, convulsions and even death due to respiratory, circulatory system failure. Therefore, strict control of the free gossypol and its derivatives is required in deep-processing process of cottonseed. In this article, according to the MSⁿ Spectra of gossypol, the structures of known and unknown gossypol derivatives were figure out by LCMS-IT-TOF. Quantity and quality of free gossypol derivatives were different when using different extracting way. The qualitative results of gossypol derivatives get from LCMS-IT-TOF could tell the best way of deep-processing process of cottonseed.