High Throughput Quantitative Analysis of Multi-mycotoxin in Beer-based Drinks using UHPLC-MS/MS

Mycotoxins often exist as contaminants in grains used in beer manufacturing. To maintain consumer needs for food safety, highly sensitive methods of detection are required by food and beverage manufactures.
UHPLC-MS/MS offers the best combination of selectivity, sensitivity, and speed for detection of these compounds in complex matrices. A high throughput method for the quantification of 14 mycotoxins in beer-based drinks was developed. While high sensitivity analysis was achieved, the nature of the analysis is characterized by a significant carry over issue as a result of the complex matrix. To enhance the robust detection of mycotoxins in beer-based drink analysis and to maintain high sensitivity, a novel autosampler technology was evaluated in this study.