LC-MS/MS analysis of the new antioxidant identified from a soft-body extract of Crassostrea gigas

A cerebral oxidation stress makes them induce insomnia and etc. So, it is desirable to take antioxidants with high penetration through blood-brain barrier (BBB) for the prevention of insomnia.
We had found a new antioxidant, 3,5-dihydroxy-4-methoxybenzyl alcohol (E6), from a soft-body extract of Crassostrea gigas, which has antioxidation ability about 2.4 times more than that of alpha-tocopherol and L-ascorbic acid and then we synthesized and identified E6.
This time, we developed the method to analyze E6 sensitively by LC-MS/MS and we verified the penetrating ability through blood-brain barrier of E6.