High-Speed Analysis of Sunitinib and Axitinib in Plasma Using Triple Quadrupole LC/MS/MS (LCMS-8050)

This article introduces an example measurement of the molecularly targeted drugs sunitinib and axitinib using the LCMS-8050 high-sensitivity triple quadrupole mass spectrometer. Although a simple method of sample pretreatment was used that involves only deproteinization, the quantitative results obtained were excellent in terms of accuracy and precision.

Content Type:
Application
Document Number:
LAAN-A-LM-E097A
Product Type:
Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Keywords:
TDM, Molecularly targeted drugs, Sunitinib, Axitinib, Plasma, Clinical research, Forensics, Pharmaceutical, Life Science, Clinical research, LCMS-8050
Language:
English
File Name:
jpo116034.pdf
File Size:
168kb

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