Rapid, high throughput quantitation of cyanotoxins in natural water by UHPLC-MS-MS
Cyanotoxins are toxins produced by bacteria called cyanobacteria (also known as blue-green algae). Cyanobacteria are found in lakes and in the ocean where they can reproduce exponentially to form blooms. The most prevalent cyanotoxin is the hepatotoxin microcystin and it is a problem worldwide in freshwater ecosystems. The World Health Organization has set the guideline for permissible amount of the microcystin LR in drinking water at 1ug/L. The National Center for Environmental Assessment suggests a limit of 0.1 μg/L. Current EPA Method 544 requires solid phase extraction of 500 mL of sample, evaporation and reconstitution in 1 mL of methanol.
This work demonstrates a quick screening method without the use of sample fortification that greatly reduces sample prep time and meets detection requirements.
- Content Type:
- Paper
- Document Number:
- PO-CON1570E
- Product Type:
- Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
- Keywords:
- Cyanotoxins, natural water, Environment, Drinking Water, Pool Water, LCMS-8050
- Language:
- English
- File Name:
- sio115088.pdf
- File Size:
- 153kb