Analysis of 8 kinds of estrogens in environmental water by ultra high performance liquid chromatograph hybrid triple quadrupole mass spectrometer

A UHPLC-MS/MS method was developed for the determination of Estrogens in environmental water. 8 kinds of Estrogens ( Estriol, 17-alpha-Estradiol, 17a-Ethinylestradion, Estrone, 17-beta-Estradiol, Diethylstilbesterol ,hexestrol, dienestrol) were seperated by UHPLC system with a gradient elution program, and detected by Shiamdzu Triple Quadrupole MS LCMS-8030. The linear range was from 0.5 to 500 μg/L with correlation coefficients (r) more than 0.999. Retention times and peak areas results were highly reproducibility. The limit of quantification (LOQ) were less than 2 ng/L for all of Estrogens. This method is rapid, efficient and highly sensitive for quantitative analysis of 8 Estrogens in environmental water.