Aggregates Sizer Enables Evaluation of Biopharmaceutical Additives to Inhibit Protein Aggregation
The Aggregates Sizer Aggregation Analysis System for Biopharmaceuticals (referred to as Aggregates Sizer hereafter) is useful for improving efficiency of formulation studies because a large number of analytes can be processed in the time taken to perform a single measurement, which is only a few seconds. We here introduce a study in which we confirmed the differences in the ability of each additive to inhibit protein aggregation, by using Aggregates Sizer to measure the concentrations of aggregate formation in protein solutions containing different additives that have repeatedly been frozen and thawed.
- Content Type:
- Application
- Document Number:
- LAAN-A-PT-E008
- Product Type:
- Particle Size Analysis
- Keywords:
- Aggregates Sizer TC, Biopharmaceuticals, Aggregation, Biopharmaceutical additives, sub-visible particle, qLD method, IgG, γ-globulin, Pharmaceutical, Life Science, Aggregates Sizer
- Language:
- English
- File Name:
- jpi517001.pdf
- File Size:
- 1,235kb