Cleaning Validation by TOC Analyzer with Easy Wiper

In the pharmaceutical industry, "cleaning validation" where residues on manufacturing equipment are quantitated to verify whether the amount is within tolerance, has been a valuable criterion for quality control and safety. In past Application News which introduced the swab sampling - direct combustion method, a piece of quartz glass filter paper was used as the swab sampling material. New swab material, Easy wiper, made of quartz glass fibers which leaves no fragments on swabbed surfaces was developed to realizer more useful method for cleaning validation, and here we introduce the analysis with Shimadzu TOC using Easy wiper.