Drug Metabolism (ADME, DMPK)

Shimadzu offers many types of the solutions to accelerate the drug development process for the earliest launching on the pharmaceutical market. Flexible and user-friendly systems are available to meet the users' needs.

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Ultra-Fast LC front-end system for high throughput screening MS

Ultra-Fast LC front-end system for high throughput screening MS

As the demand for higher throughput increases,shorter run times and higher sensitivity analyses become increasingly important.
The use of Prominence UFLC can improve both analysis efficiency and sensitivity. The lowest sample carry-over on the market is another highly advantageous feature. It contributes cost-savings to the lab and therefore reduces investment.


Metabolite Identification LCMS-IT-TOF system

Metabolite Identification LCMS-IT-TOF system

The LCMS-IT-TOF with MetID Solution software is an integrated approach to metabolite identification which maximizes the information from data-dependent high mass accuracy MSn acquisitions and accelerates effective reporting using a novel approach based on statistical data.


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Automated on-line sample pretreatment LC system

Automated on-line sample pretreatment LC system

Co-Sense for Bio Analysis is an on-line sample pretreatment system for biological samples. Deproteinization and concentration followed by dilution processes improve efficiency, reduce cost and increase sensitivity.


Multi-vendor software control compatibility

Multi-vendor software control compatibility

Multi-vendor software control compatibility Prominence series are universally compatible with multi-vendor software for LC/MS and LC/MS/MS, including Analyst® (Applied Biosystems), Xcalibur®(Thermo Scientific).
This can accelerate bioanalysis studies using MS and MSMS systems with extremely near-zero sample carry-over.


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