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Mass Spectrometry Glossary

Charge transfer reaction

In various types of generated molecular ions (M+., [M+H]+, [M-H]-, [M+Na]+, etc.), this term describes chemical bond breakage occurring at locations apparently far removed from the charge or unpaired electron. Since molecular structure information is often reflected in CID spectra and other results, the charge-remote fragmentation concept is often used in structural analysis. Since bond breakage generally occurs through the introduction of charge or unpaired electrons, normally bonds near charges and un-paired electrons are broken.