Nexera UC Prep

Choose the optimal configuration for your application

Stacked Fraction Purification System
supports injection volumes up to 20 mL for high flow rates

This system is optimized for high preparative flowrates that involve repeatedly injecting compounds which may contain several components. It can be optimized not only for chiral compounds but also achiral compounds. The FRS-40SF unit includes both injector and fraction collector functionality, so that the same unit can be used for repeated sample injections and gram-level preparative work. It supports injection volumes up to 20 mL* and ten recovery columns. Compatible with flow rates from 10 to 150 mL/min and 10 to 30 mm I.D. columns. *optional

Stacked Fraction Purification System

Multi-Fraction Purification System
for multiple peak fractionation of impurities and natural substances

This system is suitable for preparative tasks involving samples with many peaks detected, such as impurities in pharmaceuticals. Volumes of up to 2 mL* can be injected using an autosampler that holds up to 162 samples (using 1.5 mL vials). Three rack types can be selected for the FRC-40 fraction collector, which can recover up to 540 fractions (using 10 mL vials). With support for flow rates from 10 to 150 mL/min, columns with an internal diameter from 10 to 30 mm can be used. *optional

Small Volume Preparative System
Analysis & low flow rate compatibility in one system

This system is intended for analysis-scale flowrates for applications that only require fraction volumes up to a few mg (used to check synthesis for example). By connecting an FRC-40 fraction collector to the Nexera UC system, the system can seamlessly perform everything from analysis to preparative work. With a flow rate range of up to 5 mL/min, analysis-scale columns can be used.

 
 
 
 Product lineup
 
  Stacked Fraction Purification System Multi-Fraction Purification System Small Volume Preparative System
Flow rate range   10.0~150.0 mL/min 10.0~150.0 mL/min 0.0001~5.0 mL/min
Supported columns I.D:10mm~30mm
Length:up to 250mm
I.D.:10mm~30mm
Length:up to 250mm
I.D.:2.0~4.6mm
Length:up to 250mm
Injection unit
No. of samples processed: 1
Max. injection volume: 2 mL
(optional: 20 mL)
No. of samples processed:
252 (with 1 mL sample vial plate)
162 (1.5 mL sample vial plate)
84 (4 mL sample vial plate)
36 (10 mL sample vial plate)
72 (microtube plate)
288 (96-well microplate)
1,152 (384-well microplate)
Max. injection volume: 500 μL
(optional: 2 mL)
No. of samples processed:
175 (with 1-mL sample vial plate)
105 (1.5-mL sample vial plate)
50 (4-mL sample vial plate)
192 (96-well microplate)
768 (384-well microplate)
192 (96-well deep-well plate)
768 (384-well deep-well plate)
Max. injection volume: 5 μL
(optional: 20 μL)
Recovery
Supported containers: Bottles (screw-top: GL45)
Quantity: Five 100 mL to 2 L
Recovery method: Valve switching
(10 collection + 1 waste or 5 collection + 5 waste)
Supported containers: Test tubes
Quantity: 540 10-mL, 20 250-mL, or 12 500-mL test tubes
Test tube I.D.: From 10 mm
Recovery method: Arm action
Supported containers: Test tubes
Quantity: 540 10-mL, 20 250-mL,
or 12 500-mL test tubes
Test tube I.D.: From 10 mm
Recovery method: Arm action
Volume recovered per analysis
(approx.)
Up to 1 g (for 30 mm I.D. column)
Up to 1 g (for 30 mm I.D. column)
Up to 20 mg
(for 4.6 mm I.D. column)
Sample temperature
control range
No temperature control
4~45°C 4~40°C
Support functions Dedicated preparative software,
stacked injection,
parameter changing during analysis
Dedicated preparative software,
stacked injection,
parameter changing during analysis
Dedicated preparative software,
parameter changing during analysis
 

Compatible with multiple detectors (max. 4 channels)

If only the UV signal is used as a trigger in the preparative workflow, components with low UV absorption are difficult to separate and there is also a risk of accidentally fractionating unseparated components in the same detection channel. By using the MS signal as the trigger, high-purity fractions can be recovered simply by specifying the m/z value of the target components.

For Research Use Only. Not for use in diagnostic procedures.

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