Application Systems


Prominence UFPLC
Ultra Fast Preparative and Purification Liquid Chromatograph

Prominence UFPLC inherits the breakthrough fraction trapping and purification technology at the core of Crude2Pure and expands on it to provide a comprehensive on-line automated purification process

Comprehensive Two-Dimensional Liquid Chromatograph

The comprehensive 2D-LC methodology is a paradigm shift in liquid chromatography separation analysis. By combining two independent separation modes orthogonally in combination with a dual-loop/dual-valve alternate switching design, the highest possible peak capacity is achieved for LC chromatography separation.

Preparative Chromatography Systems

Shimadzu has installed more than 2000 preparative HPLC systems throughout the world, and remains committed to improving the purity and speed of separation and making this technique more cost effective. Using our broad experience and technologies at various scales and in diverse fields, we have significantly enhanced the performance that can be obtained from preparative HPLC.


The Crude2Pure system, which is based on ground-breaking purification methods, provides a new approach that reduces the work of the purification/powderization process after preparation.

Amino Acid Analysis System

The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and with high sensitivity quantitate the amino acids contained in samples with high levels of contaminants.

UF-Amino Station
LC/MS Ultra Fast Amino Acid Analysis System

Jointly developed by Shimadzu and Ajinomoto Co., Inc., it features a special-purpose, fast analysis column and a LCMS-2020 mass spectrometer, which supports ultra-fast analysis speeds, to achieve the simultaneous analysis of 38 amino acid and amino acid-related components* in just nine minutes. Additionally, it automates the derivatization reaction to eliminate the need for cumbersome pretreatment procedures by manual operation. UF-Amino Station is an excellent tool for the analysis of food products, such as meat and fermented foods containing many impurity components, and for the biochemical analysis of culture fluid.

Perfinity iDP
Integrated Protein Digestion HPLC

The Perfinity iDP (Integrated Digestion Platform) automates the protein analysis workflow from protein digestion to HPLC separation and MS detection, significantly reducing sample preparation times and enhancing reproducibility.

Online Sample Preparation
Co-Sense Series

Online Sample Preparation The Co-Sense series features automatic sample processing systems intended to improve the efficiency of LC-NMR and LC-MS operations by automating complicated sample processing steps. This eliminates the need for tedious, time-consuming, and expensive manual processes.

Inert LC system

The Inert LC system is now part of Prominence series.
Featuring the same high reliability, robustness, and expandability as the Prominence series, this system is ideal for the analysis of biopolymers such as antibody drugs.

Bromate Analysis System

This system can be used either for analyzing bromates in drinking water using the tribromate ion method or for analyzing residual bromates in food products using the o-dianisidine method, and enables quantitation of trace quantities of bromates with high sensitivity and precision. * * System configurations may vary depending on the reaction method.

Cyanic Analysis System

Cyanic Analysis System is a post-column visible light absorption detection system compliant with the Drinking Water Test Method. It enables high-sensitivity simultaneous analysis of cyan and cyanogen chloride by their chemical form.

Gel Permeation Chromatography System

Gel permeation chromatography (GPC) is essential in polymer chemistry for measuring the distribution of molecular weights. Shimadzu has introduced the Prominence GPC system, designed specifically to provide superior data reliability and ease of use.

GPC Cleanup System

This system is a GPC cleanup pretreatment system that is compliant with the ministry method of rapid pesticide analysis. It efficiently separates pesticide components from fats, dyes, and other substances contained in agricultural product extracts and automatically collects them in fractions.

Reducing Sugar Analysis System

Shimadzu's unique post-column fluorescence detection method (Japanese patent) with arginine as the reagent, is a highly sensitive and selective method for sugars. This system is suitable for the analysis of complex samples, like fermentation products, and for ultra trace analysis, such as determination of sugar components in glycoprotein.

Organic Acid Analysis System

Shimadzu's unique post-column pH-buffered electroconductivity method is ideal for the selective and highly sensitive detection of organic acids. Compared to conventional methods, such as the UV short wavelength method or a simple conductivity method, this system improves quantitation reliability.

SEC(GPC)-AccuSpot-AXIMA System

MALDI-MS is widely used as an analytical tool for the characterization of synthetic polymer samples. However, in complex mixtures, the minor components may not be detected due to ion suppression by more abundant species also present in the sample. Gel Permeation Chromatography (GPC)-MALDI is an effective method for detailed analysis of such samples.

Nexera FV
Ultra High Performance Liquid Chromatograph for Online Dissolution Testing

The Nexera FV provides substantial labor savings by automating processes ranging from the dispensing of dissolution media to data acquisition and data analysis.

For Research Use Only. Not for use in diagnostic procedures.

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