Shim-pack Bio Series
Solution for Analysis of Peptides, Oligonucleotides and Biopharmaceuticals
The accurate analysis of biopharmaceuticals compounds is required for developing higher quality biopharmaceuticals. Shim-pack Bio Diol, IEX and HIC columns will improve the accuracy of the characterization of peptides, oligonucleotide and biopharmaceuticals.
Shim-pack Bio Diol : Size Exclusion Chromatography Columns
With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates.
|Shim-pack Bio Diol||Diol-60||Diol-120||Diol-200||Diol-300|
|Particle Size||3 μm，5 μm||2 μm，3 μm，5 μm|
|Pore Size||6 nm||12 nm||20 nm||30 nm|
|pH Range||5.0 - 7.5|
|below 10,000||1,000 - 100,000||5,000 - 300,000||20,000 - 1,000,000|
Shim-pack Bio IEX : Ion Exchange Chromatography Columns
Shim-pack Bio IEX Columns are available in Q (quaternary ammonium) and SP (sulfopropyl) chemistries and are based on porous (Q and SP columns) and non-porous (Q-NP and SP-NP columns) hydrophilic polymers with low nonspecific adsorption. The porous particles offer excellent binding capacity with exceptionally high efficiency and the non-porous particles offer high efficiency and exceptional resolution.
Analysis of Synthesized Oligonucleotide (Single Strand DNA) using Shim-pack BIO IEX Q-NP
|Shim-pack Bio IEX||Q-NP||SP-NP||Q||SP|
|Particle||hydrophilic non-porous polymer||hydrophilic non-porous polymer|
|Particle Size||3 μm，5 μm||5 μm|
|pH Range||2 - 12|
Shim-pack Bio HIC：Hydrophilic Interaction Chromatography
Shim-pack Bio HIC Column is a hydrophobic interaction chromatography (HIC) column packed with butyl bonded hydrophilic nonporous polymer particles (4μm). HIC is suitable for the separation of anlaytes with slightly different hydrophobicity, such as antibody-drug conjugate (ADC) with different drug-antibody ratios (DAR). Shim-pack Bio HIC can be used for the analysis of DAR of ADC with relatively low pressure and high resolution.
|Shim-pack Bio HIC|
|Particle Size||4 µm|
|4.6 x 100mm||227-31174-01|