Shim-pack Scepter LC Columns

Shim-pack Scepter Chemistries

Method Scouting

Utilize excellent stability & performance under a wide range of LC conditions

With excellent stability under a wide range of LC conditions, Shim-pack Scepter LC columns are effective for method scouting combining mobile phase pH and organic modifier.

【 Comparison of Chromatograms using Gradient condition with Acetonitrile 】

  C18 HD-C18 C8 Phenyl PFPP
pH
2.9
pH
6.1
pH
9.9
 
Outside of
recommended pH
 

Analytes

1. Saccharin (pKa = 2.2)

2. Dextromethorphan (pKa = 8.3)

3. Amitriptyline (pKa = 9.4)

4. N-Butyl paraben (pKa = 8.3)

5. Ibupurofen (pKa = 4.4)

For Research Use Only. Not for use in diagnostic procedures.

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