Preparative system general HPLC: Nexera Prep

Capable of High Purity Preparation Triggered by up to Four Detector Channel Signals

 

Using MS Signal Triggers Enables Recovery with no Target Fraction Omissions

It can be difficult to prepare low UV absorptive components using just a UV signal as the trigger, so there is a risk that the fraction will be missed.
By using the MS signal as the trigger, the preparative work can be performed simply, with nothing missed. By specifying the m/z of the target component, fractions can be collected with confidence. The LCMS-2020 mass spectrometer enables high-sensitivity and high-resolution detection for preparative work with no target components omitted.

UV Detection Chromatogram /  MS Detection Chromatogram

High Purity Recovery of Target Components Using Multiple Signal Triggers

By combining up to four detector signal channels, target components can be recovered at high purity levels.

High Purity Recovery of Target Component A

The MS signal from the detection of target component A is used as the trigger to start fraction collection. The MS signal from the detection of impurity B, which is eluted in proximity, is used as the trigger to stop fraction By combining multiple triggers in this way, it is possible to recover only the target component at high purity level. Combining a variety of detector signals as triggers, targets can be recovered at high purity levels, with the confidence that all peaks were detected.

 

Optional Analytical and Preparative Open Solution™ Software Simplifies
Preparative Operations and Data Analysis

Efficient System Sharing via Open Access

Open Access

Open Solution simplifies the sharing of preparative systems between several people.


There is a special sample registration window, so preparative work can be performed easily just by having users log in and then specify their method, injection volume and target m/z.

Preparative Operations and Data Analysis can be Performed from a Single Window

With the Open Solution data browser, preparative results can be checked from a single window.
When the test tubes are selected, the peaks are highlighted, and the MS spectrum and UV spectrum for the applicable peak are displayed.
The information for the fractionated compound can be checked easily.

Sample and Fraction Information are aggregated in a Single Window

* This is compatible with the FRC-10A.

 

For Research Use Only. Not for use in diagnostic procedures.

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