Analysis of Mycotoxins

Mycotoxins are chemical products produced in fungus and are toxic to humans, animals, and crops. There are more than 300 known mycotoxins, including aflatoxin, deoxynivalenol, patulin, fumonisin and others, and some of them are strictly controlled under regulations. HPLC and LC-MS are mainly used for analysis of mycotoxins, and simultaneous analysis of multiple mycotoxins has been carried out for more efficient screening.

Simultaneous Analysis of 25 Mycotoxins (LC-MS/MS)

LC-MS/MS is effective for analysis of mycotoxins in complex matrices. Shown is an example of the simultaneous analysis of 25 mycotoxins by LC-MS/MS and the Method Package for Mycotoxins. All compounds, including positive and negative ions, were separated and detected with high sensitivity within 12 minutes. For analysis of mycotoxins with high sensitivity, eliminating carryover is indispensable. Modified rinse methods using the SIL-30AC autosampler can eliminate carryover of fumonisins.

かび毒25成分の高速一斉分析

High-speed simultaneous analysis of 25 mycotoxins

 
 
 
 
 
Registered Methods 
 
Method
Number of
Components
Analysis
Time (min)
Simultaneous Analysis of 25 Mycotoxins
25 15
Simultaneous Analysis with High Sensitivity
16 30
Patulin Analysis
1 10
Aflatoxins Analysis
6 30
Trichothecenes Analysis
4 12
Fumonisins Analysis
3 15
10 mycotoxins using APCI
10 33

Simultaneous Analysis of Mycotoxins (LC)

Integrated HPLC Nexera-i

Integrated HPLC
Nexera-i

Simultaneous analysis of mycotoxins is important because multiple mycotoxins have been detected in a single food and may cause a synergistic effect. From this background, simultaneous analytical methods have been developed. Shown below are chromatograms of direct analysis of aflatoxins without any derivatization and rapid screening of 10 mycotoxins using HPLC.

Analysis of aflatoxins without TFA derivatization (N = 5)

Analysis of aflatoxins without TFA derivatization (N = 5)

Simultaneous analysis of 10 mycotoxins

Simultaneous analysis of 10 mycotoxins

 

Main Applications

Related Information (Including Old Applications)

For Research Use Only. Not for use in diagnostic procedures.

This page may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.

Top of This Page