Analysis of Residual Pesticides in Crude Drugs – GC
Analysis of Pesticides in Asian Ginseng
A number of crude drugs derived from plants are cultivated, and pesticides are sometimes used to prevent pest damage. As with residual pesticides in foods, residual pesticides in crude drugs must also be carefully considered as a safety issue.
Residual pesticides in crude drugs can be analyzed using a gas chromatograph equipped with ECD after performing extraction, concentration, and cleanup as a pretreatment.
Here is an example of the analysis of pesticides in Asian ginseng.
A gas chromatograph (GC) measures the content of various components in a sample. The sample solution injected into the instrument enters a gas stream, which transports the sample into a separation tube known as the "column." Helium or nitrogen is used as this so-called carrier gas. The various components are separated inside the column, and a detector measures the quantity of the components that exit the column. To measure a sample with an unknown concentration, a standard sample with a known concentration is injected into the instrument. The standard sample peak retention time (appearance time) and area are compared to the test sample to calculate the concentration.