Liquid Chromatograph Mass Spectrometer
High-Speed Ion Polarity Switching Mode
High-speed ion polarity switching can be specially useful when it cannot be judged whether samples will be detected as positive or negative ions. The LCMS-IT-TOF utilizes a newly developed, highly accurate and stable power supply as well as a newly developed high-voltage switch that allows for polarity switching in only 0.1 sec or less (necessary for the sharp HPLC peaks available with the advances in high-speed chromatography). The maximum rate for polarity switching is 2.5 Hz, which allows for a pair of positive and negative ion MS spectra to be obtained 2.5 times per second.