[ WHITE PAPER ] On the Accurate Understanding of Mass Measurement Accuracy in Q-TOF MS

High-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matrix and to allow identification of compounds by measuring their accurate masses. The key performance attribute underlying all application fields is mass measurement accuracy (MMA) as it affords molecular specificity and reduction of false positive results. This white paper focuses on the fundamentals of MMA in terms of ion statistics. Various factors affecting the observed MMA will be explained, revealing the engineering rationale behind Shimadzu LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer for stably achieving sub-ppm MMA.

Content Type:
Paper
Document Number:
C10G-E073
Product Type:
Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry, Quadrupole time-of-flight (Q-TOF) mass spectrometer
Keywords:
Mass Spectrometry, MS; Quadrupole Time-of-flight, Q-TOF; Mass Measurement Accuracy, MMA; High-Resolution Accurate-Mass, HRAM; High-Resolution Mass Spectrometry, HR-MS, Food and Beverages, Pharmaceutical, Life Science, LCMS-9030
Language:
English
File Name:
C10G-E073
File Size:
1,118kb

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For Research Use Only. Not for use in diagnostic procedures.

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