Procedures for Creating MRM Methods for Multicomponent Simultaneous Analyses Using Retention Indices

To create MRM analysis methods, it is necessary to configure the analysis time program based on the retention times for the target compounds. However, when creating multicomponent simultaneous analysis methods for more than 100 components, considerable time and effort is needed to analyze all the standards, and calculate the retention times.
The GCMSsolution control software (ver. 4.20 and later) for the GCMS-TQ series is equipped with a Smart MRM method creation function. Smart MRM is linked to the AART (Automatic Adjustment of Retention Time) function, and calculates retention times for the measured components from just a single n-alkane analysis. In addition, an analysis time program is configured automatically based on the calculated retention times. This Data Sheet introduces the procedures for creating these MRM methods for multicomponent simultaneous analysis.