On-line LC-GCxGC-MS/MS: A Powerful Unified Separation-science Tool
This Technical Report demonstrates the potential of the on-line combination of high performance liquid chromatography (HPLC), cryogenically modulated comprehensive two-dimensional gas chromatography (GCxGC), and triple quadrupole mass spectrometry (MS/MS). The selectivity of the HPLC dimension enabled the separation of chemical classes; each fraction, transferred to the GCxGC instrument via a syringe-based interface, was subjected to a specific programmed temperature vaporizer (PTV) GCxGC-MS/MS untargeted or targeted analysis.
- Content Type:
- Application
- Document Number:
- C146-E271
- Product Type:
- Mass Spectrometry, Gas Chromatograph-Mass Spectrometry
- Keywords:
- liquid-gas chromatography, comprehensive gas chromatography, triple quadrupole mass spectrometry, Coal Tar, Hydrocarbon Processing Industry (Petrochemical, Chemical), 5D Ultra-e
- Language:
- English
- File Name:
- jpo214101.pdf
- File Size:
- 599kb