BAC Analysis Utilizing GCMS and FID Combined with Fully Automated Sample Prep Performed by Robotic Sampler
Blood Alcohol Content (BAC) analysis by gas chromatography (GC) and gas chromatography/mass spectrometry (GCMS) is a standard analytical technique that has been around for years. However, the standard and sample prep is laborious and tedious. Using a custom script and robotic autosampler with syringe swap capability, a protocol was developed to automatically prepare calibration and check standards, perform internal standard addition, and perform headspace (HS) injections into a GCMS paired with FID establishing a turn key system for BAC analysis.
In this study, the quantitative accuracy and reproducibility of four analytes were tested with a Shimadzu GCMS/FID with AOC-6000 multifunction robotic autosampler.
- Content Type:
- Paper
- Document Number:
- PO-CON1883E
- Product Type:
- Gas Chromatography, Gas Chromatograph-Mass Spectrometry, Mass Spectrometry
- Keywords:
- Blood Alcohol Content, Pharmaceutical, Life Science, AOC-6000
- Language:
- English
- File Name:
- sio219061.pdf
- File Size:
- 471kb