Fully automatized LC-MS/MS analysis of neuroleptics using a novel sample preparation system

Neuroleptics also known as antipsychotics are a class of drug used for medication primarily used to manage psychosis. Their active principle is influencing the synaptic conduction in the central nervous system. Their precise quantitation for therapeutic purpose is necessary as for several class of drugs like antidepressants, benzodiazepines, anti-epileptics… Such analysis are mainly done by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) with multi-analytes approach nowadays. In order to streamline the workflow, we demonstrate here the use of a novel fully automated sample preparation system coupled online with LC-MS/MS.

*Not available in the U.S.

Content Type:
Paper
Document Number:
PO-CON1785E
Product Type:
Liquid Chromatography, Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Keywords:
neuroleptics, Clinical research, Forensics, Healthcare, Clinical research, Forensics, Toxicology, Drug test, CLAM-2000, LCMS-8045, Nexera X2
Language:
English
File Name:
ego117120.pdf
File Size:
1,114kb

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For Research Use Only. Not for use in diagnostic procedures.

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