Direct analysis of 10 antipsychotics in serum by the online system integrating solid-phase extraction with UHPLC-MS/MS

A fully-automatic system integrating solid-phase extraction with ultra-high performance liquid chromatography-tandem mass spectrometry was successfully applied to the direct analysis of ten antipsychotics in serum.

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Mass Spectrometry, Liquid Chromatograph-Mass Spectrometry
serum, antipsychotics, LC-MS/MS method, blood sample, liquid-liquid extraction (LLE), solid-phase extraction (SPE), fully-automatic system integrating SPE with UHPLC-MS/MS, Food and Beverages, Pharmaceutical, Life Science, Healthcare, Development (Formulation, Scale-up, Method development), Drug discovery, SPE-UHPLC-MS/MS system
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