Development of a Comprehensive Detection Method of Eicosanoids and Platelet Activating Factor Using Ultra-High Performance Liquid Chromatography/Mass Spectrometry
Using LCMS-8040, simultaneous detection method of eicosanoids and PAF was developed. 54 MRM transitions for 50 eicosanoids and PAF (platelet activation factor) were optimized. Limit of quantitation for several targets was in the subpicogram range.
*Not available in the U.S.
- Content Type:
- Application
- Document Number:
- C146-E219
- Product Type:
- Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
- Keywords:
- Eicosanoids, Lipid Mediator Molecules, Kinetex C8, Positive/Negative Ion-Switching, Clinical research, Forensics, Healthcare, Pharmaceutical, Life Science, DMPK, ADME, Safety testing, LCMS-8040
- Language:
- English
- File Name:
- jpo113111.pdf
- File Size:
- 794kb
