High-Sensitivity Determination of Catecholamines in Plasma Using the LCMS-8060 Triple Quadrupole LC/MS/MS

Catecholamines are a family of signaling molecules found in brain, adrenal medulla and other nervous systems. Catecholamines i n plasma, namely norepinephrine (NE), epinephrine (EP) and dopamine (DA), are commonly measured in clinical research. Analysis of catecholamines in plasma requires both high sensitivity and high throughput. Presented here is a platform designed to demonstrate the capability to detect catecholamines in plasma, comprising multiplexed plasma sample preparation by Biotage EVOLUTE WCX solid phase extraction followed by high-sensitivity quantitation by LCMS-8060.

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Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Catecholamines, Norepinephrine, Epinephrine, Dopamine, Plasma, Biotage EVOLUTE WCX, MAqC-ODS, Clinical research, Forensics, Healthcare, Pharmaceutical, Life Science, Toxicology, Drug test, LCMS-8060
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