Analysis of Cold Medicine Using Newly Developed "Shim-pack MAqC-ODS I" Column

Use of the Shim-pack MAqC-ODS I column makes it possible to achieve retention of highly polar basic compounds without the use of ion-pair reagents in the mobile phase, thereby permitting the application of gradient elution. As a result, improved sensitivity and time savings can be achieved in the simultaneous analysis of highly polar basic compounds and other substances. Here, using the Shim-pack MAqC-ODS I column, we introduce an example of analysis focusing on substances that are typically included as active ingredients in over-the-counter cold medicines.