Management of the mobile phase is of great importance in high-performance liquid chromatograph analysis. Depletion of the mobile phase during analysis not only results in failure of the analysis, but also risks damaging expensive analytical columns. To prevent these problems, it is necessary to estimate the amount of mobile phase required for analysis before starting, but such an estimate is laborious to calculate, especially with regards to gradient elution. There is also the possibility that the mobile phase may nonetheless be depleted during analysis due to a calculation error. While, it is time-consuming for the user to visit the laboratory frequently to check the quantity of mobile phase remaining. In this report we describe the effectiveness of the Mobile Phase Monitor Module (MPM-40) for real-time measurement of mobile phase quantity and automated estimate of consumption of mobile phase with LabSolutions™.