Heightened Analytical Efficiency and Integrated Management of Multifaceted Data Using the Dual Injection Function in the SIL-40 Series Autosampler

The unique dual injection function is optionally available for the Nexera series. At analysis sites, there are cases in which analysis must be performed twice under different analytical conditions because multiple components from a single sample cannot be separated at the same time, or two completely different compounds must be quantified. With the dual injection system, two independent flow lines are built into a single platform. Chromatograms are acquired simultaneously under two different conditions, and the results obtained are integrated into a single data file. Examples of such analyses include fermentation monitoring, which involves the simultaneous measurement of organic acids and amino acids, the metabolites of microorganisms, as well as the test of complex impurity property in the drug that are hard to separate at the same time under a single set of conditions. In these analyses, this function not only significantly improves analytical efficiency, but also integrates the two chromatograms into a single data file, ensuring traceability with respect to the sample. Additionally, not only the data files but also the method files and batch files are each integrated respectively into a single file, simplifying data management, and ensuring data integrity.
In this article, we introduce the actual process starting with how to use the dual injection system, as well as the sequence of steps up to integrated data management, and the heightening of efficiency.