Highly sensitive and rapid analysis of synthetic dyes in sea food by LC/MS/MS

Synthetic dyes like malachite green, crystal violet are used for wide range of industrial applications. However, they are also used in aquaculture due to their anti-bacterial and anti-fungal properties. They are cheap, very effective and readily available, but due to their toxic effects to humans, these dyes are banned in the EU and US regions with zero tolerance policy.
Here, LC/MS/MS method has been developed for quantitation of malachite green, leucomalachite green, crystal violet and leucocrystal violet from sea food sample using LCMS-8045, a triple quadrupole mass spectrometer from Shimadzu Corporation, Japan.