A new device for direct QuEChERS salts extraction: application to drugs of abuse in blood, urine and oral fluid
Extraction procedures using QuEChERS consist of manually adding salts to the analyzed matrix, previously mixed in a polar solvent (acetonitrile, ACN). This approach is largely employed for pesticides residues but also for multiples classes of drugs.
- In this study, we explored the performance of a QuEChERS extraction based on a new pre-packed kit containing 100 mg of salts (Micro Volume QuEChERS; MVQ) and compared it to a previously validated procedure, routinely used in a clinical lab.
The example of an LC-MS method for the analysis of 44 Drugs Of Abuse (DOA) using this new device is presented.
- Content Type:
- Paper
- Document Number:
- PO-CON1865E
- Product Type:
- Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
- Keywords:
- QuEChERS, blood, urine, oral fluid, Clinical research, Forensics, Pharmaceutical, Life Science, Forensics, Toxicology, Drug test, LCMS-8060
- Language:
- English
- File Name:
- fro119036.pdf
- File Size:
- 211kb
