Determination of Industrial Dyes in Food by LCMS-IT-TOF

MS3 data of basic and acidic industrial dyes were obtained by LCMS-IT-TOF, and an MS3 database for basic industrial dyes and acidic industrial dyes had been created.
The linear range for 10 basic industrial dyes was from 1.0 to 100 μg/L, and linear responses were observed with coefficients (r) more than 0.99. The limits of quantification (LOQ) for the method were 1.5-2.0 μg/kg. The linear range for 9 acidic industrial dyes was from 0.01 to 4 mg/L, and linear responses were observed with coefficients (r) more than 0.99. The limits of quantification (LOQ) for the method were 0.02-0.2 mg/kg.