Analysis of Phenols in Drinking Water Using Triple Quadrupole LC/MS/MS (LCMS-8040)

Phenols can be formed as wastewater purification and disinfectant by-products, and Japan's Ministry of Health, Labour and Welfare have designated six phenols, including phenol, 2-chlorophenol, 4-chlorophenol , 2,4-dichlorophenol, 2,6-dichlorophenol, and 2,4,6-trichlorophenol as subject to water quality standards requirements. The method designated (by the ministry notification) for analysis of these six phenol components is solid-phase extraction-derivatization -GC/MS.
Here, we introduce an example of phenol analysis by UHPLC/MS/MS. Unlike the use of GC/MS for this analysis, LC/MS/MS does not require derivatization, and therefore simplifies the analysis process.