Analysis of Steroids and NSAIDs Using the Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer

Drugs that are registered as prohibited substances mainly fall into the categories of anabolic steroids (AAS) used primarily for building muscle strength, steroidal anti-inflammatory drugs for their anti-inflammatory and immunosuppressive effects, and narcotic and designer drugs. Also, non-steroidal anti-inflammatory drugs (NSAIDs) are drugs used to treat pain and inflammation as well as fever, and although they are not specified as prohibited drugs, their abuse by athletes is being viewed as a problem due to their side effects.
Here we introduce an accurate identification method for typical steroidal and non-steroidal anti-inflammatory drugs using multiple reference ion ratios, in addition to an example of high-sensitivity measurement.