Application of Metabolomics to Microbial Breeding

Metabolomics presents useful tools for the evaluation of metabolic changes during microorganism breeding, and for understanding metabolic changes related to a target material and its precursors and intermediates. By deepening our understanding of the metabolic pathways involved in material production, metabolomics is expected to result in more efficient materials production. In this article, we discuss an example of LC/MS analysis of how the sulfur-containing metabolites vary during culture of a cysteine-producing Escherichia coli when either thiosulfuric acid or sulfuric acid is added as the sulphur source during cysteine synthesis.

Content Type:
Application
Document Number:
LAAN-A-LM-E102
Product Type:
Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Keywords:
Metabolomics, Microbial breeding, Sulfur metabolism, Metabolic pathway, Culture, Simultaneous analysis, Pharmaceutical, Life Science, Metabolomics, LCMS-8040, LCMS-8050
Language:
English
File Name:
jpo116074.pdf
File Size:
803kb

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