A Multiomics Approach Using Metabolomics and Lipidomics

By evaluating metabolic changes caused by metabolomics and combining the results of lipidomics targeting phospholipids, we attempted to understand metabolic changes caused by a complex omics approach. The following is an example of an evaluation of metabolic changes in Escherichia coli, which efficiently produces ergothioneine, a sulfur-containing metabolite, using a metabolomics and lipidomics approach when a sulfur source used in the synthesis of cysteine as a substrate is added.

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Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Cells, Escherichia coli, cells, media, fermentation, substance production, sulfur sources, metabolites, lipids, phospholipids, metabolomics, lipidomics, metabolic fluctuations, ergothionein, Pharmaceutical, Life Science, Metabolomics, DMPK, ADME, Safety testing, LCMS-8060
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