A Multiomics Approach Using Metabolomics and Lipidomics

By evaluating metabolic changes caused by metabolomics and combining the results of lipidomics targeting phospholipids, we attempted to understand metabolic changes caused by a complex omics approach. The following is an example of an evaluation of metabolic changes in Escherichia coli, which efficiently produces ergothioneine, a sulfur-containing metabolite, using a metabolomics and lipidomics approach when a sulfur source used in the synthesis of cysteine as a substrate is added.

Content Type:
Application
Document Number:
LAAN-A-LM-E127
Product Type:
Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Keywords:
Cells, Escherichia coli, cells, media, fermentation, substance production, sulfur sources, metabolites, lipids, phospholipids, metabolomics, lipidomics, metabolic fluctuations, ergothionein, Pharmaceutical, Life Science, Metabolomics, DMPK, ADME, Safety testing, LCMS-8060
Language:
English
File Name:
jpo119018.pdf
File Size:
410kb

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