Simultaneous Analysis of Etizolam, Triazolam, and Their Metabolites in Biospecimens Using LCMS-9030

We simultaneously analyzed Etizolam, Triazolam, and their metabolites using the LCMS-9030, a high-resolution mass spectrometer. Since these psychotropic drugs cannot be separated only using liquid chromatography (LC), we separated these drugs by difference in the accurate mass and selectively performed qualitative and quantitative analyses by diluting the samples serially. Good calibration curve results were obtained and stable and accurate relative mass errors were achieved.

Content Type:
Application
Document Number:
LAAN-A-LM-E153
Product Type:
Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
Keywords:
Benzodiazepine, Psychotropic drugs, Metabolite, QuEChERS method, HRMS, Clinical research, Forensics, Pharmaceutical, Life Science, LCMS-9030
Language:
English
File Name:
jpo119019.pdf
File Size:
186kb

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