Characterisation of a PEG Conjugated Medicine; Polymer Analysis Using the MALDI-8020 Benchtop Linear MALDI-TOF Mass Spectrometer

Polymers play important roles in various fields. Among analytical techniques for polymer analysis including SEC/GPC chromatography and NMR/FT-IR spectroscopy, MALDI mass spectrometry is a very popular technique.
This article introduces the analysis of vitamin E-TPGS (vitamin E tethered to PEG1000 succinate), which is used as a carrier molecule for the delivery of pharmaceutical agents, using the MALDI-8020 benchtop linear MALDI-TOF mass spectrometer and PolymerixTM polymer analysis software.

Content Type:
Application
Document Number:
LAAN-A-TM-E049
Product Type:
Mass Spectrometry, Life Science Lab Instruments, MALDI-TOF Mass Spectrometry
Keywords:
Polymer, Monomer, Benchtop linear MALDI-TOF mass spectrometer, Matrix-assisted laser desorption/ionization, Time-of-flight mass spectrometer, End group, Repeating unit, Adduct, Polymerix, Analysis software, Pharmaceutical agent carrier, Vitamin E, Hydrocarbon Processing Industry (Petrochemical, Chemical), Pharmaceutical, Life Science, Rubber, Resin, Plastics, MALDI-8020
Language:
English
File Name:
jpo318013.pdf
File Size:
775kb

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For Research Use Only. Not for use in diagnostic procedures.

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