MALDI-in source decay for the detection of methionine oxidation using the MALDI-8020 benchtop linear MALDI-TOF mass spectrometer
Here, were we demonstrate the capability of the MALDI-8020 benchtop linear TOF mass spectrometer to determine the methionine oxidation (Met-O) of Exendin-4 peptide through accurate intact mass analysis and top-down sequencing. This can be a potentially valuable tool in the QC environments to pinpoint undesired changes during the production process.
- Content Type:
- Application
- Document Number:
- LAAN-A-TM-E048
- Product Type:
- Mass Spectrometry, Life Science Lab Instruments, MALDI-TOF Mass Spectrometry
- Keywords:
- MALDI-TOF mass spectrometer, methionine oxidation, In-Source Decay(ISD), Exendin-4 peptide, Pharmaceutical, Life Science, MALDI-8020
- Language:
- English
- File Name:
- jpo318014.pdf
- File Size:
- 1,160kb
