The Development of Miniature MALDI Digital Ion Trap Mass Spectrometer

To analyze the structure of the bio-molecules, a large and expensive MS equipment is necessary as TOF/TOF, etc. We have reported a digital ion trap mass spectrometer (DIT-MS) which is driven by high-voltage rectangular waveform for trapping ions, and developed several DIT-based MS instrument which have specific functions such as wide mass range ion scanning and rapid digital asymmetric waveform isolation (DAWI) of the precursor by adapting our driving unit of rectangular waveform. The advantage of utilizing rectangular waveform is that the frequency and the duty ratio of the waveform can be changed easily and flexibly. However, the DIT itself, as well as the mass spectrometer system has kept the similar size as the conventional one.