Analysis of Lipids in a NAFLD Model Mouse
Mass spectrometry is used frequently in lipid research not only for blood and urine samples, but also when using laboratory animal organs as samples. In recent years, using multivariate analysis of homogenate samples in conjunction with measuring distributions in tiss ue section samples is expected to accelerate research work involved in identifying disease mechanisms or discovering new drugs. Therefore, this example analyzes the variations in lipid components after administering 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) to a non-alcoholic fatty liver disease (NAFLD) model mouse.
- Content Type:
- Application
- Document Number:
- C146-E266
- Product Type:
- Mass Spectrometry, Life Science Lab Instruments, Liquid Chromatograph-Mass Spectrometry, Imaging, Imaging Mass Microscope, MALDI-TOF Mass Spectrometry
- Keywords:
- MS imaging, iMScope, lipids, Pharmaceutical, Life Science, DMPK, ADME, Safety testing,Drug discovery, iMScope TRIO, LCMS-IT-TOF, AXIMA Confidence
- Language:
- English
- File Name:
- jpo714089.pdf
- File Size:
- 1,388kb