Analysis of Lipids in a NAFLD Model Mouse

Mass spectrometry is used frequently in lipid research not only for blood and urine samples, but also when using laboratory animal organs as samples. In recent years, using multivariate analysis of homogenate samples in conjunction with measuring distributions in tiss ue section samples is expected to accelerate research work involved in identifying disease mechanisms or discovering new drugs. Therefore, this example analyzes the variations in lipid components after administering 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) to a non-alcoholic fatty liver disease (NAFLD) model mouse.

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Mass Spectrometry, Life Science Lab Instruments, Liquid Chromatograph-Mass Spectrometry, Imaging, Imaging Mass Microscope, MALDI-TOF Mass Spectrometry
MS imaging, iMScope, lipids, Pharmaceutical, Life Science, DMPK, ADME, Safety testing,Drug discovery, iMScope TRIO, LCMS-IT-TOF, AXIMA Confidence
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