Shim-pack GISS Series - Features

HPLC Column Solutions

High-speed analysis with ultra-high inertness and high durability

Analysis Examples

β-blocker

Peaks (100 μg/L each)

   Q1 > Q3
 1. Acebutolol  337.10 > 116.05 (+)
 2. Atenolol  267.25 > 145.00 (+)
 3. Labetalol  329.00 > 161.95 (+)
 4. Nadolol  310.05 > 254.00 (+)
 5. Pindolol  249.80 > 116.00 (+)

 

Conditions

 Column  Shim-pack GISS C18 (50 mmL x 2.1 mmI.D., 1.9 μm)
 Eluent  A) 10 mM Ammonium Formate in H2O
 B) 10 mM Ammonium Formate in CH3OH
 A/B = 70/30 ‒ 0.3min - 40/60 ‒ 0.5min - 0/100 ‒ 0.1min ‒ 0/100 ‒ 0.01min -70/30 ‒ 0.5min - 70/30, v/v
 Flow Rate  0.6 mL/min
 Col. Temp.  40 °C
 Detection  LC/MS/MS(ESI, Positive, Negative MRM)

Specifications

  Shim-pack GISS C18
Bonded Phase Octadecyl Groups
Analysis Mode Reversed Phase
Features High-speed analysis with ultra-high inertness and high durability
Particle Size (μm) 1.9, 3, 5
Pore Size (nm) 20
Surface Area (m2/g)
200
Carbon Loading (%) 9
End Cap
pH Range 1-10
USP Code L1