1. Shimadzu announces the release of the LCMS-8045RX, LCMS-8050RX, and LCMS-8060RX triple quadrupole high-performance liquid chromatograph mass spectrometers globally. The three models in the LCMS-TQ RX Series carry onward the basic functionality of Shimadzu triple quadrupole (TQ) liquid chromatograph mass spectrometers (LC-MS) while providing even higher stability and convenient operability. Shimadzu is releasing this series for manufacturers and contract analysis organizations in the pharmaceutical, environmental, and food product sectors.

   In the pharmaceutical, environmental, and food product sectors, regulations have become stricter, and there is an increasing demand to obtain reliable data with highly stable instruments. In particular, the global market for LC-MS/MS instruments with their high sensitivity and selectivity is expected to grow by at least 8 % annually, and the objectives and sectors where they are applied have diversified. In routine analysis applications, which account for 40 % of the LC-MS/MS market, several samples are measured consecutively, so data reliability and shortened downtime areimportant. In addition to basic performance, such instruments must provide both stability and operability.

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   With the LCMS-TQ RX Series, the data reliability has been heightened by stabilizing the sample ionization with the ion source improved. This series is equipped with functions that check the instrument status prior to measurements, and automatically implement calibration (tuning), as well as ecology mode for minimizing standby power consumption, thereby achieving high-efficiency laboratory operations with a low environmental impact. Through this series, Shimadzu will heighten the efficiency of laboratory work related to pharmaceuticals, food product development, and environmental inspection so that we contribute to the growth of research and development in healthcare, green transformation, and other sectors.

   

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Features

1. 1. Improving Data Reliability with High Stability and Measurement Sensitivity

   In the LCMS-TQ RX Series, the ion source is equipped with the newly developed CoreSpray nozzle. The stability of the analysis data has been increased by uniformizing the sample spray with improving the shape of the nozzle used to nebulize the sample. Moreover the ionization efficiency of some compounds has been improved by raising the upper limit of nebulizing gas flow rate.

   CoreSpray

   CoreSpray technology applied to the repeated analysis of pesticides in black tea matrix resulting in enhanced robustness (%RSD less than 3.5%, 20,000 injections). Data were acquired without internal standards and without diverting to waste for the initial polar matrix effects.

   • Learn more about LCMS-TQ RX Series

2. 2. Maintaining Favorable Instrument Conditions, Heightening the Efficiency of Laboratory Operations

   The PERFORMANCE CONCIERGE function checks the mass accuracy, spectral intensity, and other instrument conditions before starting measurements, and automatically implements tuning depending on the results. Consistently maintaining the instrument in optimal condition controls the tuning times and reduces downtime.

   Instrument Check

3. 3. Minimization of Power Consumption by the Instrument itself, and Reducing Load on the Lab and the Environment

   In ecology mode, the instrument monitors its usage, and if it has not been used for a set period, it automatically shuts down. Conventionally, the inside of the instrument continues to be heated even after measurements are finished. By minimizing this, power consumption is reduced by approximately 31 %.

   Comparison of Power Consumption