STEP Temperature (˚C) Time (min) Power (W)
1 50 2 1000
2 30 3 0
3 180 25 1000
4 150 1 0
5 180 4 1000
6 180 15 1000
Application
News
No.J120
Inductively Coupled Plasma Mass Spectrometry
Analysis of Minerals and Harmful Elements
in Formula Milk Powder Using ICPMS-2030
LAAN-A-CP-E033
Q Introduction
Formula milk powder is formulated to contain a good
balance of minerals necessary for infant growth.
Japan's Health Promotion Law includes stipulations on
the essential mineral content, including calcium (Ca),
iron (Fe), and copper (Cu), of food for special dietary
use (e.g., formulated milk powder for infants) and
requires the labeling of their content.
1)
Harmful elements like lead (Pb) have a negative effect
on infant development, and require strict safety
controls from raw materials to the finished product.
We describe using Shimadzu's ICPMS-2030 inductively
coupled plasma mass spectrometer to perform a
simultaneous analysis of elements present in formula
milk powder (National Metrology Institute of Japan
certified reference material [NMIJ CRM]). In addition to
being highly sensitive, the ICPMS-2030 uses a helium
gas collision system that greatly reduces the spectral
interference caused by argon and chlorine.
[References]
1) Permission standards for labeling and component composition of
breast milk and formulated milk powder for infants (Permission for
labeling of food for special dietary use, Food Labeling Division,
Consumer Affairs Agency, No. 221 of March 31, 2016)
Q Sample
NMIJ CRM milk powder (for trace element analysis)
(NMIJ CRM 7512-a: No. MI-040)
Q Sample Preparation
Compared to the normal wet digestion method, the
microwave sample decomposition method has the
advantages of completing decomposition in a shorter
period of time and within a closed system, which results
in little volatilization loss of As and other analytes. We
used the ETHOS One (Milestone General K.K., Japan) to
perform sample decomposition.
After placing a sample 0.25 g, hydrochloric acid 0.5 mL,
and nitric acid 6.5 mL in a quartz decomposition vessel,
decomposition was performed using a microwave
sample pretreatment system.
After decomposition, pure water was added to make
up 250 mL of solution for analysis (1000-fold dilution).
At this point, Sc, Co, Ga, Y, In, and Ti internal standard
elements were added (to an analytical solution
concentration of 10 μg/L).
Table 1 shows the decomposition conditions.
Table 1 Decomposition Conditions for Microwave
Digestion System
Q Instrument and Analytical Conditions
Shimadzu's ICPMS-2030 inductively coupled plasma
mass spectrometer was used for analysis. Analytical
conditions are shown in Table 2.
In addition to being highly sensitive, the ICPMS-2030
uses a helium gas collision system that greatly reduces
the spectral interference caused by argon and chlorine.
Instrument : ICPMS-2030
High-frequency output : 1.2 kW
Plasma gas flowrate : 8.0 L/min
Auxiliary gas flowrate : 1.10 L/min
Carrier gas flowrate : 0.60 L/min
Sample introduction : Nebulizer 10
Chamber : Cyclone chamber (electronic cooling)
Plasma torch : Mini-torch
Collision gas : He
Table 2 Analytical Conditions
