Shimadzu Review Vol.75 [3・4] (2018) | Development of Advanced Core Technology

SPECIALLY COLLECTED PAPERS

Development of New LC Detector Using Ion Mobility Technique

by Akiko Imazu1, Yoshinori Arita1, Motohide Yasuno, Ph.D.2, Hiroshi Tanaka3,
Toshiya Habu4, Yoshihito Yuasa5, and Kiyoshi Ogawa1
(Received January 15, 2019)

Abstract

We have developed a new detector that achieves high sensitivity and multi-purpose properties for liquid chromatographs using ion mobility spectrometry. Characterized by rapid separation capability of separating ions on the basis of their sizes and structures, it is expected to be used for analyzing a wide variety of samples. Measurements were performed in order to evaluate sensitivity and resolution of the new instrument, and sensitivity of 30 pg in caffeine detection and resolution of 70 for sucrose by the ion mobility spectrometer were achieved. It is also capable of detecting a wide range of compounds with high sensitivity.

Keywords: LC, Ion mobility, Detector

1Electron/Ion Unit, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan

2Bio-Industry Unit, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan

3Analytical & Measuring Instruments Division, Life Science Business Department LC Business Unit, Shimadzu Corporation, Kyoto, Japan

4Analytical & Measuring Instruments Division, X-Ray/Surface Business Unit, Shimadzu Corporation, Kyoto, Japan

5Corporate Product Design Center, Development Support Unit, Shimadzu Corporation, Kyoto, Japan

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